Synthesis of 1-N-ethylsisomicin: a broad-spectrum semisynthetic aminoglycoside antibiotic

1 January 1976

journal article
research article
Published by Royal Society of Chemistry (RSC) in Journal of the Chemical Society, Chemical Communications

No. 6,p. 206-208
https://doi.org/10.1039/c39760000206

Abstract

Site-selective reductive N-alkylation of aminoglycoside antibiotics related to gentamicin is described and the structure of the products and of related compounds is unambiguously established using circular dichroism and mass spectrometry.

Keywords

SPECTRUM