Subnanomolar wirksame Inhibitoren aus dem Computerscreening: eine Modellstudie an der humanen Carboanhydrase II
- 19 January 2001
- journal article
- research article
- Published by Wiley in Angewandte Chemie
- Vol. 113 (2) , 404-408
- https://doi.org/10.1002/1521-3757(20010119)113:2<404::aid-ange404>3.0.co;2-z
Abstract
No abstract availableKeywords
This publication has 21 references indexed in Scilit:
- How many leads from HTS?Drug Discovery Today, 1999
- Virtual screening—an overviewDrug Discovery Today, 1998
- Structure and mechanism of carbonic anhydrasePharmacology & Therapeutics, 1997
- What Can We Learn from Molecular Recognition in Protein–Ligand Complexes for the Design of New Drugs?Angewandte Chemie International Edition in English, 1996
- Was läßt sich aus der molekularen Erkennung in Protein‐Ligand‐Komplexen für das Design neuer Wirkstoffe lernen?Angewandte Chemie, 1996
- The New Genomics: Global Views of BiologyScience, 1996
- Neighborhood Behavior: A Useful Concept for Validation of “Molecular Diversity” DescriptorsJournal of Medicinal Chemistry, 1996
- Structural basis of inhibitor affinity to variants of human carbonic anhydrase IIBiochemistry, 1995
- Comparison of Automatic Three-Dimensional Model Builders Using 639 X-ray StructuresJournal of Chemical Information and Computer Sciences, 1994
- Positions of His‐64 and a bound water in human carbonic anhydrase II upon binding three structurally related inhibitorsProtein Science, 1994