Effects of Human Recombinant Erythropoietin on Anaemia, Systemic Haemodynamics and Renal Function in Predialysis Renal Failure Patients
- 1 January 1989
- journal article
- research article
- Published by Oxford University Press (OUP) in Nephrology Dialysis Transplantation
- Vol. 4 (11) , 966-970
- https://doi.org/10.1093/ndt/4.11.966
Abstract
Seven anaemic patients with predialysis chronic renal failure were treated with human recombinant erythropoietin. Anaemia was improved, with a 31% increase in haematocrit, but blood pressure increased in all patients with an average of 12% in systolic (PPPP<0.05). It is suggested that blood pressure elevation might be developed as a result of volume expansion, elevated cardiac output, and increased total peripheral resistance.Keywords
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