Effect of glucose limitation and specific mutations in the module 5 enoyl reductase domains in the nystatin and amphotericin polyketide synthases on polyene macrolide biosynthesis

This publication has 18 references indexed in Scilit:

• Chemical Diversity of Polyene Macrolides Produced by Streptomyces noursei ATCC 11455 and Recombinant Strain ERD44 with Genetically Altered Polyketide Synthase NysC
  Antimicrobial Agents and Chemotherapy, 2004
• Site-specific Mutagenesis and Domain Substitutions in the Loading Module of the Nystatin Polyketide Synthase, and Their Effects on Nystatin Biosynthesis in Streptomyces noursei
  Journal of Biological Chemistry, 2003
• How do the polyene macrolide antibiotics affect the cellular membrane properties?
  Published by Elsevier ,2003
• Polyene antibiotic biosynthesis gene clusters
  Applied Microbiology and Biotechnology, 2002
• The candicidin gene cluster from Streptomyces griseus IMRU 3570 The GenBank accession numbers for the sequences reported in this paper are AJ300302 and AJ300303.
  Microbiology, 2002
• A complex multienzyme system encoded by five polyketide synthase genes is involved in the biosynthesis of the 26-membered polyene macrolide pimaricin in Streptomyces natalensis
  Chemistry & Biology, 2000
• Biosynthesis of the polyene antifungal antibiotic nystatin in Streptomyces noursei ATCC 11455: analysis of the gene cluster and deduction of the biosynthetic pathway
  Chemistry & Biology, 2000
• An erythromycin analog produced by reprogramming of polyketide synthesis.
  Proceedings of the National Academy of Sciences, 1993
• Modular Organization of Genes Required for Complex Polyketide Biosynthesis
  Science, 1991
• Physico-chemical and microbiological comparison of nystatin, amphotericin A and amphotericin B, and structure of amphotericin A.
  The Journal of Antibiotics, 1985