The Fixed Eruption

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Abstract
Un médecin vous guérit de la colic; deux médecins vous guérissent de la médecine (One physician cures you of the colic; two physicians cure you of the medicine). Although disseminated skin eruptions caused ^by drugs are regrettably common, those that appear only in one or a very few places, the socalled fixed eruptions, occur relatively infrequently. If the medicament responsible for the latter type is repeated at sufficiently long intervals, the eruption will heal either completely or partially, but will reappear in the same place with each renewed exposure to the offending drug or other agent. Thus the term "fixed" has an anatomic and not a temporal meaning. Brocq,1who wrote the classic article on the subject, is generally credited with defining thiscondition, although Archer2described such eruptions earlier. A number of agents capable of causing fixed eruptions are listed in the table. Characteristics The lesion, which

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