Procedures for the assay of carbenicillin in body fluids.
- 1 February 1970
- journal article
- Vol. 19 (2) , 264-7
Abstract
The assay of carbenicillin in clinical specimens is complicated by the fact that carbenicillin also contains a small amount of benzylpenicillin, thereby precluding the use of conventional penicillin assay organisms. This report gives details of a microbiological assay method involving the use of a strain of Pseudomonas aeruginosa which is very sensitive to carbenicillin but insensitive to benzylpenicillin. The outline of a microassay method with this organism is presented, and a method for the assay of specimens containing mixtures of carbenicillin and other antibiotics is described.This publication has 8 references indexed in Scilit:
- Carbenicillin Therapy of Gram-Negative Bacilli InfectionsThe Lancet Healthy Longevity, 1969
- Laboratory and clinical studies of carbenicillin against gram-negative bacilli.1968
- Carbenicillin: a new semisynthetic penicillin active against Pseudomonas pyocyanea.BMJ, 1967
- New Semi-synthetic Penicillin active against Pseudomonas pyocyaneaNature, 1967
- CLINICAL AND LABORATORY STUDIES WITH CARBENICILLIN A New Penicillin Active against Pseudomonas pyocyaneaThe Lancet, 1967
- Carbenicillin, a new semisynthetic penicillin active against Pseudomonas aeruginosa.1967
- The Role of Penicillin Acylase in the Resistance of Gram-Negative Bacteria to PenicillinsJournal of General Microbiology, 1966
- The Paper-Disc Agar-Plate Method for the Assay of Antibiotic Substances.1945