Enantioselective Synthesis of Allylic AlcoholsviaAsymmetric [2,3]-Sigmatropic Meisenheimer Rearrangement
- 1 January 1994
- journal article
- letter
- Published by Georg Thieme Verlag KG in Synlett
- Vol. 1994 (11) , 969-971
- https://doi.org/10.1055/s-1994-23068
Abstract
Various allylic alcohols 6 are prepared in high enantiomeric excesses (ee = 93 - 99 %) by oxidation of readily available allylamines 3 bearing a C2-symmetrical amine moiety, followed by a [2,3]-sigmatropic Meisenheimer rearrangement of the resulting amine-N-oxide 4 and reductive N,O-bond cleavage of hydroxylamines 5.Keywords
This publication has 0 references indexed in Scilit: