Aldehyde reductase is a major protein associated with 3-deoxyglucosone reductase activity in rat, pig and human livers
- 1 November 1991
- journal article
- Published by Portland Press Ltd. in Biochemical Journal
- Vol. 279 (3) , 903-906
- https://doi.org/10.1042/bj2790903
Abstract
3-Deoxyglucosone reductase activity in the extracts of rat, pig and human livers was potently inhibited by aldehyde reductase inhibitors. The major species of 3-deoxyglucosone reductase purified from human and pig livers were biochemically and immunochemically identical with aldehyde reductase. The two enzymes and rat liver aldehyde reductase exhibited higher catalytic efficiency for 3-deoxyglucosone than for D-glucuronate, a representative substrate of aldehyde reductase.Keywords
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