The genetics of autistic disorders and its clinical relevance: a review of the literature
Top Cited Papers
- 10 October 2006
- journal article
- review article
- Published by Springer Nature in Molecular Psychiatry
- Vol. 12 (1) , 2-22
- https://doi.org/10.1038/sj.mp.4001896
Abstract
Twin and family studies in autistic disorders (AD) have elucidated a high heritability of the narrow and broad phenotype of AD. In this review on the genetics of AD, we will initially delineate the phenotype of AD and discuss aspects of differential diagnosis, which are particularly relevant with regard to the genetics of autism. Cytogenetic and molecular genetic studies will be presented in detail, and the possibly involved aetiopathological pathways will be described. Implications of the different genetic findings for genetic counselling will be mentioned.Keywords
This publication has 259 references indexed in Scilit:
- Serotonin transporter gene promoter polymorphism and autism: A family-based genetic association study in Japanese populationBrain & Development, 2006
- Absence of coding mutations in the X‐linked genes neuroligin 3 and neuroligin 4 in individuals with autism from the IMGSAC collectionAmerican Journal Of Medical Genetics Part B-Neuropsychiatric Genetics, 2006
- Mutation analysis of methyl-CpG binding protein family genes in autistic patientsBrain & Development, 2005
- Absence of causative mutations and presence of autism-related allele in FOXP2 in Japanese autistic patientsBrain & Development, 2005
- Angelman syndrome: is there a characteristic EEG?Brain & Development, 2005
- Analysis of the autism chromosome 2 linkage region: GAD1 and other candidate genesNeuroscience Letters, 2004
- Association and transmission analysis of the FMR1 IVS10 + 14C-T variant in autismAmerican Journal of Medical Genetics, 2003
- RETRACTED: Ileal-lymphoid-nodular hyperplasia, non-specific colitis, and pervasive developmental disorder in childrenThe Lancet, 1998
- Organization of the human serotonin transporter geneJournal Of Neural Transmission-Parkinsons Disease and Dementia Section, 1994
- Behavioral consequences of congenital rubellaThe Journal of Pediatrics, 1978