Xanthine Oxidase in Pair-Fed Rats on Diets Marginally Deficient in Lysine

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Abstract
Male weanling rats were placed on zein-base diets supplemented with 0.25%, 0.50%, and 1.00% lysine. All experimental groups were pair-fed with the group receiving the lowest amount of lysine (0.25%) and maintained on their respective diets for 42 days. A marked decrease in liver xanthine oxidase activity per unit of liver protein, and in total liver protein, occured in the 0.25% group. The animals in the 0.5% group showed reduction in liver protein but not in xanthine oxidase activity, when compared with the animals receiving the 1.0% lysine supplement.