Abstract
To the Editor: A 37-year-old woman who delivered her first child in June 2002 presented in September 2002 with an axillary mass, a fever, and chills. A biopsy revealed an anaplastic large-cell lymphoma of the T-cell type, positive for the hybrid protein ALK, with cytoplasmic as well as nuclear staining associated with the t(2;5) translocation.1 The tumor involved the mediastinal and left axillary nodes and the skin. The patient was treated with cyclophosphamide, doxorubicin, vincristine, etoposide, and prednisone but had progressive disease in the central nervous system, as confirmed by radiology, and cells that were positive for ALK in the . . .

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