Regulation of Rat Renal (Na++K+)-Adenosine Triphosphatase Activity by Triiodothyronine and Corticosterone*

Publisher Website
Google Scholar
Abstract
The effects of corticosterone and T3 [triiodothyronine] on renal cortical and outer medullary NaK-ATPase activities in the rat were studied. Corticosterone increases cortical and outer medullary NaK-ATPase activities when administered as either a single or multiple doses. Corticosterone and T3 are known to enhance NaK-ATPase activity. The possibility of interaction between the effects of corticosterone and T3 on renal NaK-ATPase activity was investigated. Corticosterone and T3 regulate renal cortical NaK-ATPase activity via parallel independent pathways, and corticosterone appears to regulate medullary NaK-ATPase activity without participation by thyroid hormone.

This publication has 0 references indexed in Scilit: