Is home‐based administration of prostaglandin safe and feasible for medical abortion? Results from a multisite study in Vietnam

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Abstract
To study the efficacy and acceptability of a simplified medical abortion regimen in Vietnam. Open-label study. One peri-urban and three urban hospitals and four urban maternal-child health family planning clinics located in Northern, Central and Southern Vietnam. A total of 1601 women seeking abortion services from January 2001 to December 2001. Consenting women presenting for abortion services with gestations less than 56 days LMP who met the inclusion criteria were given 200 mg mifepristone and offered the choice of either home or clinic administration of 400 microg oral misoprostol two days later. Complete abortion rate of 89.2% (n= 1395), with 1.5% (n= 24) of the women lost to follow up. The majority of women (>90%) reported that their medical abortion experience was either 'very satisfactory' or 'satisfactory'. There was a strong preference for home administration of misoprostol, with more than four-fifths of the study population selecting to administer the prostaglandin at home. Location of misoprostol administration did not affect efficacy rate. Regardless of location selected, women expressed a high degree of satisfaction with the medical abortion experience. Medical abortion with the option of home administration of misoprostol is safe and feasible for introduction into the Vietnamese healthcare system.