THE SUGAR TOLERANCE IN SIBLINGS OF JUVENILE DIABETIC PATIENTS
- 28 July 1934
- journal article
- research article
- Published by American Medical Association (AMA) in JAMA
- Vol. 103 (4) , 240-242
- https://doi.org/10.1001/jama.1934.02750300014005
Abstract
It is generally accepted that diabetes mellitus is a familial or hereditary disorder of metabolism. In fact, Pincus and White1have been able statistically to show that diabetes is inherited as a mendelian recessive characteristic. Experimental proof of this fact has been brought forward by Cammidge.2He was able, by mating strains of mice having a high fasting blood sugar with those having normal blood sugars, to transmit the hyperglycemia to succeeding generations as a recessive quality. Cammidge suggested that in human beings the same blood sugar conditions might occur. Joslin and his co-workers3have shown that new cases of diabetes mellitus are continually being encountered in the families of diabetic children. They have shown a progressive incidence in new cases in those families from year to year. Because of the familial tendency of diabetes, a study was started in 1928 with the purpose of detecting earlyKeywords
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