Presence of Anti‐c in the Serum of 42 Women Giving Birth to c Positive Babies: Serological and Clinical Findings1

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Abstract
During routine ante‐natal testing during the period 1953–73 anti‐c was found in the serum of 63 women. Twenty‐four of them had received blood transfusion previously and of these 22 were multigravidae. In 39 women pregnancies alone were responsible for the immunization. The anti‐c titres of the 42 women giving birth to c positive babies showed that the probability of developing haemolytic disease increases with higher titres. But low titres by no means exclude the existence of such disease. Among the 42 c positive babies 32 had a positive direct antiglobulin test. Some of the affected infants had a serious degree of haemolytic disease.