HISTOLOGIC ANALYSIS OF PHOTO-CHEMICAL LESIONS PRODUCED IN RHESUS RETINA BY SHORT-WAVE-LENGTH LIGHT

  • 1 January 1978
    • journal article
    • research article
    • Vol. 17  (10) , 1029-1035
Abstract
The photopathology of retinal lesions produced by extended exposure (1000 s) to low corneal power levels (62 .mu.W) of blue light (441 nm) was investigated by light microscopy in 20 rhesus eyes over an interval ranging from 1 h-90 days after exposure. Results indicate a nonthermal type of photochemical lesion originating in the retinal pigment epithelium and leading to a histological response with hypopigmentation which requires 48 h to appear. This type of lesion helps to explain solar retinitis and eclipse blindness and has significance for aging and degenerative changes in the retina.

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