THE EFFECTS OF SERUM ON SPERMATOZOA
Open Access
- 20 March 1947
- journal article
- research article
- Published by Rockefeller University Press in The Journal of general physiology
- Vol. 30 (4) , 321-335
- https://doi.org/10.1085/jgp.30.4.321
Abstract
A spermicidal factor was found in fresh human, bovine, rabbit, guinea pig, and rat sera. It kills the spermatozoa of its own species (except in the case of human serum) and the sperms of other species. It was unstable, thermolabile, and of large molecular size. It was present in limited quantity in the fresh serum and could be used up by a definite number of spermatozoa. It could be destroyed by sodium citrate, by Seitz filtration, by trypsin, and by snake venom. This factor was not present in tissue extracts and various plasma protein fractions. The strength or concentration of this factor varies in different individuals and in different species. This factor has several characteristics similar to those of complement.This publication has 3 references indexed in Scilit:
- Sperm production of a pony stallion and the treatment of spermatozoa in vitro with special reference to artificial insemination of maresThe Journal of Agricultural Science, 1943
- Superovulation in rabbitsThe Anatomical Record, 1940
- Fecundity of male rabbits as determined by “dummy matings”The Journal of Agricultural Science, 1938