Muscle and Liver Glycogen of Mouse Strains Susceptible or Resistant to Nutritionally Induced Obesity

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Abstract
Muscle and liver glycogen levels of mice differing in their susceptibility to nutritionally induced obesity were studied in relation to inherited differences in metabolic and endocrine patterns. The I/Fn strain, resistant to nutritional obesity, is characterized by a muscle glycogen level 4 to 6 times higher than those of strains which can be made obese. The liver glycogen of the I strain mouse is significantly lower than those of the other strains. Muscle glycogen levels were found to reach a maximum at about 6 months of age in all but one of our strains.

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