Erythropoietin enhances hippocampal long-term potentiation and memory
Open Access
- 9 September 2008
- journal article
- Published by Springer Nature in BMC Biology
- Vol. 6 (1) , 37
- https://doi.org/10.1186/1741-7007-6-37
Abstract
Erythropoietin (EPO) improves cognition of human subjects in the clinical setting by as yet unknown mechanisms. We developed a mouse model of robust cognitive improvement by EPO to obtain the first clues of how EPO influences cognition, and how it may act on hippocampal neurons to modulate plasticity.Keywords
This publication has 51 references indexed in Scilit:
- Recombinant Human Erythropoietin in the Treatment of Human Brain Disease: Focus on CognitionJournal of Renal Nutrition, 2008
- Improvement of cognitive functions in chronic schizophrenic patients by recombinant human erythropoietinMolecular Psychiatry, 2006
- Involvement of Protein Synthesis and Degradation in Long-Term Potentiation of Schaffer Collateral CA1 SynapsesJournal of Neuroscience, 2006
- Emerging biological roles for erythropoietin in the nervous systemNature Reviews Neuroscience, 2005
- The Developing Synapse: Construction and Modulation of Synaptic Structures and CircuitsScience, 2002
- Short-Term Synaptic PlasticityAnnual Review of Physiology, 2002
- Erythropoietin Prevents Place Navigation Disability and Cortical Infarction in Rats with Permanent Occlusion of the Middle Cerebral ArteryBiochemical and Biophysical Research Communications, 1998
- Definition of the Readily Releasable Pool of Vesicles at Hippocampal SynapsesNeuron, 1996
- Clustering and slow switching in globally coupled phase oscillatorsPhysical Review E, 1993
- Differential contribution of amygdala and hippocampus to cued and contextual fear conditioning.Behavioral Neuroscience, 1992