β2-Microglobulin Amyloidosis: Illustrative Cases

Abstract
Patients on long-term dialysis tend to develop amyloidosis derived from β2-microglobulin. Serum levels of this protein rise in renal insufficiency and remain high in patients on dialysis. The distribution of amyloid deposits in such patients as well as tissue diagnosis, immunohistochemistry, and electron microscopic features are briefly discussed.