Induction of Tryptophan Pyrrolase Activity in Starving Rabbits of Different Ages.

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Abstract
Summary Induction of liver tryptophan pyrrolase activity occurs readily in young rapidly growing male and female rabbits between 30-75 days of age when subjected to starvation for 24 hours or more. LTP activity in older rabbits between 4-10 months of age increases only slightly during 11 days of starvation. In the younger 30-75-day-old rabbits, intraperitoneal injection of 0.5 g L-tryp-tophan per kg body weight induces the enzyme between 7- to 15-fold over control values as compared to about 2-fold for 4-10-month-old animals.