Evidence against autorepression of the ββ′ operon in Escherichia coli
- 1 January 1976
- journal article
- research article
- Published by Springer Nature in Molecular Genetics and Genomics
- Vol. 145 (2) , 223-226
- https://doi.org/10.1007/bf00269598
Abstract
By using rifampicin to increase the rate of β and β′ synthesis in a heterodiploid strain of E. coli carrying the mutation rif pr (Km7), which codes for a rifampicin sensitive RNA polymerase to which the drug binds weakly, and the dominant mutation rif D R , which codes for a rifampicin resistant RNA polymerase, the concentration of these subunits in the cell was increased 1.6 fold. Measurements made after removal of rifampicin from the cells showed that the excess β and β′ subunits did not reduce the rate of their own synthesis below normal.This publication has 17 references indexed in Scilit:
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