COMPARISON OF TERATOGENIC ACTION OF SUBSTANCES RELATED TO PURINE METABOLISM IN MOUSE EMBRYOS
- 1 January 1972
- journal article
- Published by Elsevier in The Japanese Journal of Pharmacology
- Vol. 22 (2) , 201-206
- https://doi.org/10.1254/jjp.22.201
Abstract
Teratogenic and embryocidal actions of adenine in the mouse were demonstrated (1-2). Since adenine is an important purine metabolite in animals of all kinds as well as in plants, it was decided to investigate other purine metabolites and a xanthine oxidase inhibitor as to whether or not similar actions on developing mouse embryos could he demonstrated.Keywords
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