Lifetime Panic-Depression Comorbidity in the National Comorbidity Survey

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Abstract
EPISODE COMORBIDITY is of considerable importance because of its high prevalence1,2 and association with impairment and chronicity.3,4 Episode comorbidity between panic disorder and depression is one of the strongest psychiatric comorbidities1,5 and the single strongest anxiety-mood episode comorbidity in treatment groups6 and general population samples.7 In this report, we present epidemiological data on panic-depression comorbidity in the National Comorbidity Survey (NCS).8 Unlike clinical studies, we deal with lifetime comorbidity and focus on predictive priorities between the first onsets of these disorders to shed light on the influences that lead to panic-depression comorbidity.