THE EFFECT OF CARBON ARC RADIATION ON BLOOD PRESSURE AND CARDIAC OUTPUT

Abstract
The outstanding effect in the dog is a diminution in both blood pressure and cardiac output. In normal men the blood pressure shows a slight lowering (6 mm. systolic, 8 mm. diastolic) lasting 1 to 2 days, accompanied by an increase in cardiac output averaging 21%. The highest value for cardiac output is reached on the 2d or 3d day after irradiation with a return to normal by the 5th or 6th day. Only insignificant changes are found in O consumption. In hypertensives there is a consistent and more marked lowering particularly of the systolic blood pressure, the average drop being 17 mm. for the systolic and 7 mm. for diastolic pressure. The cardiac output increased in twenty-one instances by an average of 39%, decreased in six by an average of 23%, and showed no significant change in five. The changes in O consumption and pulse rate are small and inconstant. Hemoglobin changes indicate that, as a rule, whenever the cardiac output increases there is a corresponding increase in the blood volume and when it decreases there is possibly a diminution in blood volume.

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