PROGESTERONE BLOCKADE OF ESTROGEN-INDUCED LH RELEASE IN ANESTRUAL EWES

Abstract
A release of luteinizing hormone (LH) was induced in anestrual ewes following an injection of 50 μg or 1 mg estradiol-17 β (E2). Daily injections of 30 mg progesterone, ending 4 h before estrogen, were completely effective in blocking the induced LH release if begun at least 1 day before 50 μg E2 or 3 days before 1 mg E 2. Ewes releasing LH had an accompanying release of follicle-stimulating hormone.

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