Treatment of drug‐induced agranulocytosis with recombinant GM‐CSF
- 1 November 1990
- journal article
- case report
- Published by Wiley in Journal of Internal Medicine
- Vol. 228 (5) , 537-539
- https://doi.org/10.1111/j.1365-2796.1990.tb00275.x
Abstract
A 53-year male patient, treated for rheumatoid arthritis with sulphasalazine, developed a total agranulocytosis. When this state had prevailed for at least 10 d no bone marrow granulocyte progenitor cells were detectable. Intravenous GM-CSF treatment was initiated 5 d later, and the patient recovered within the next 6 d. GM-CSF treatment for severe agranulocytosis deserves further investigation.Keywords
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