Surfing with the tunicates into the post-genome era
Open Access
- 15 October 2005
- journal article
- review article
- Published by Cold Spring Harbor Laboratory in Genes & Development
- Vol. 19 (20) , 2407-2411
- https://doi.org/10.1101/gad.1365805
Abstract
This year is the centenary of Edward G. Conklin's signal findings in embryology: the elucidation of complete cell lineages and the discovery of localized maternal determinants. Conklin used ascidian embryos to elucidate universal principles in embryology. A century later, ascidians, or sea squirts, have not only entered the post-genome era, but in many ways are leading the way to the promise of a “systems-level” understanding of complex processes such as notochord formation, neurogenesis, and even behavior.Keywords
This publication has 21 references indexed in Scilit:
- Uncoupling heart cell specification and migration in the simple chordateCiona intestinalisDevelopment, 2005
- De novo discovery of a tissue-specific gene regulatory module in a chordateGenome Research, 2005
- An Integrated Database of the Ascidian, Ciona intestinalis: Towards Functional GenomicsZoological Science, 2005
- A Genome-Wide Survey of Genes for Enzymes Involved in Pigment Synthesis in an Ascidian, Ciona intestinalisZoological Science, 2005
- Gene expression profiles of transcription factors and signaling molecules in the ascidian embryo: towards a comprehensive understanding of gene networksDevelopment, 2004
- The ascidianMespgene specifies heart precursor cellsDevelopment, 2004
- Morpholino-based gene knockdown screen of novel genes with developmental function inCiona intestinalisDevelopment, 2003
- Ciona intestinalis: an emerging model for whole-genome analysesTrends in Genetics, 2003
- The Draft Genome of Ciona intestinalis : Insights into Chordate and Vertebrate OriginsScience, 2002
- Miniature Genome in the Marine Chordate Oikopleura dioicaScience, 2001