Purification and Characterization of GP90, One of the Envelope Glycoproteins of Respiratory Syncytial Virus
- 1 April 1984
- journal article
- research article
- Published by Microbiology Society in Journal of General Virology
- Vol. 65 (4) , 761-767
- https://doi.org/10.1099/0022-1317-65-4-761
Abstract
The large glycoprotein, GP90, of respiratory syncytial virus (RSV) was purified by affinity chromatography using a monoclonal antibody. Hyperimmune rabbit antiserum directed specifically to the purified GP90 neutralized RSV to high titre but did not inhibit fusion of previously infected cells. 125I-labelled GP90 bound rapidly to HEp-2 cells in an unsaturable manner; binding was inhibited by the hyperimmune rabbit antiserum.This publication has 20 references indexed in Scilit:
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