Degradation of DNA by Intense, Noncavitating Ultrasound

Abstract
As an initial study of the interaction of intense sound waves and macromolecules, solutions of DNA were irradiated with noncavitating, 1-Mc/sec ultrasound at intensities in the neighborhood of 30 W/cm2. Sedimentation-velocity analysis of the molecular weight of the DNA suggests that relative motion between the macromolecules and the suspending medium may be the mechanism by which degradation occurs.

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