Modeling Chlorine Inactivation Requirements ofCryptosporidium parvumOocysts
- 1 September 1997
- journal article
- research article
- Published by American Society of Civil Engineers (ASCE) in Journal of Environmental Engineering
- Vol. 123 (9) , 865-875
- https://doi.org/10.1061/(asce)0733-9372(1997)123:9(865)
Abstract
Chlorine and monochloramine inactivation of Cryptosporidium parvum oocysts was studied using bench-scale experiments in 0.05-M phosphate buffer at pH 6 and 8 at 22°C. Animal infectivity using neonatal CD-1 mice was used as the criterion for oocyst viability. Inactivation data were fitted to a robust kinetic model, the incomplete gamma Hom (I.g.H.) which can account for first-order disinfectant decomposition. For chloramination a two-step disinfection approach was evaluated in which chlorine species were applied sequentially with free chlorine followed by ammonium chloride and preformed monochloramine (if necessary). Increasing levels of free chlorine pretreatment were shown to reduce the subsequent monochloramine concentration and/or contact time required for a given level of inactivation thereby demonstrating synergism. Incomplete gamma Hom models were used to generate design graphs that can aid engineers in establishing disinfection requirements for controlling Cryptosporidium parvum in drinking water.Keywords
This publication has 51 references indexed in Scilit:
- Chlorine Penetration into Artificial Biofilm Is Limited by a Reaction−Diffusion InteractionEnvironmental Science & Technology, 1996
- The Infectivity ofCryptosporidium parvumin Healthy VolunteersNew England Journal of Medicine, 1995
- Effect of the method of preparing monochloramine upon inactivation of MS2 coliphage, Escherichia coli, and Klebsiella pneumoniaeCanadian Journal of Microbiology, 1992
- Cryptosporidium and waterLetters in Applied Microbiology, 1990
- Immunobiology of Cryptosporidium spp.Pathology and Immunopathology Research, 1989
- Cryptosporidium spp. and cryptosporidiosisMicrobiological Reviews, 1986
- Effect of disinfectants on survival of cryptosporidium oocystsPublished by Wiley ,1982
- Sodium alteration of chlorine equilibriums. Quantitative descriptionEnvironmental Science & Technology, 1981
- The Behavior of Chlorine as a Water DisinfectantJournal AWWA, 1948
- Viability and Destruction of the Cysts of Endameba histolyticaJournal AWWA, 1941