Placental and Foetal Metabolism of Acetaldehyde in Rat II. Studies on Metabolism of Acetaldehyde in the Isolated Placenta and Foetus

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Abstract
The aldehyde‐oxidizing capacity of placenta and foetal liver from the rat was studied using acetaldehyde as substrate. In the placenta the activity was approximately 8 % and in foetal liver 49 % of that found in the liver of adult animal. The placenta seems to prevent most of the acetaldehyde found in maternal blood during ethanol oxidation from entering the foetal circulation.