Renal imaging studies at 1.5 and 9.4 T: Effects of diuretics

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Abstract
We have studied the effects of two diuretics, selective for renal cortical (furosemide) and inner medullary (vasopressin antagonist) water handling, in rat kidney at 1.5 T and find that furosmide completely dissipates the cortical‐inner medullary T2 gradient whereas the vasopressin antagonist has little effect. This phenomenon appears to be related to changes in luminal water content. We also demonstrate the feasibility of obtaining live mouse kidney images with a resolution of 100 × 100 × 700 μm at 9.4 T. © 1988 Academic Press, Inc.