STUDY OF CO-POSITIVITY OF 3 MULTIPUNCTURE TECHNIQUES WITH INTRADERMAL PPD TUBERCULIN

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Abstract
Patients (135) with a reaction of 10 mm or more of induration to 5 TU [tuberculin units] of intradermal PPD [purified protein derivative] were simultaneously tested with 3 multipuncture techniques to determine the co-positivity of the multiple puncture methods with the Mantoux method. Of the 3 multipuncture preparations used (Tine Test, Aplitest and Mono-Vacc), the Mono-Vacc had 2 (1.5%) false-negative results after 48 h with only 1 remaining negative result after 72 h; the Tine Test had 21 (15.5%) and the Aplitest had 13 (9.6%) false-negative reactions after 48 h. Vesicular eruptions were not a commonly noted reaction to the multipuncture preparations. Of the 3 multipuncture preparations commercially available, Mono-Vacc is the preferred reagent because of its significantly lower incidence of false-negative reactions.

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