PROPERTIES OF TWO REGULATING GENES FOR ALKALINE PHOSPHATASE
- 1 February 1962
- journal article
- research article
- Published by American Society for Microbiology in Journal of Bacteriology
- Vol. 83 (2) , 297-+
- https://doi.org/10.1128/jb.83.2.297-300.1962
Abstract
Garen , A. (University of Pennsylvania, Philadelphia) and H. Echols . Properties of two regulating genes for alkaline phosphatase. J. Bacteriol. 83: 297–300. 1962.—A constitutive mutation in one of the two regulating genes for alkaline phosphatase has two effects on the synthesis of the enzyme: repression of synthesis is blocked, and the cell's capacity to produce the enzyme is reduced. The behavior of this type of mutation has been studied in heterozygotes. The results suggest that the product of this regulating gene functions as an inducer as well as a repressor.Keywords
This publication has 4 references indexed in Scilit:
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- Influence of inorganic phosphate in the formation of phosphatases by Escherichia coliBiochimica et Biophysica Acta, 1960
- Genetic and chemical studies with alkaline phosphatase of E. coli.1959
- The genetic control and cytoplasmic expression of “Inducibility” in the synthesis of β-galactosidase by E. coliJournal of Molecular Biology, 1959