Acute Febrile Neutrophilic Dermatosis Associated With Sjögren's Syndrome

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Abstract
Sweet's syndrome (acute febrile neutrophilic dermatosis)1,2 is a dermatologic syndrome that is characterized by dull red, tender plaques with a predilection for the extremities and trunk. The lesions usually resolve within a month but recurrences are not infrequent. Histological features consist of extensive perivascular polymorphonuclear (PMN) infiltrates with prominent leukocytoclasis in the papillary and upper reticular dermis. The syndrome is frequently preceded by a febrile illness and is often associated with an elevated ESR, leukocytosis, fever, and a prompt response to corticosteroids. Conjunctivitis, episcleritis, arthralgia, and arthritis may occur.2 Leukemia,3,4 seminoma,5 and metastatic adenocarcinoma6 have occurred in association with Sweet's syndrome. We report the case of a patient in whom both Sweet's syndrome and Sjögren's syndrome developed simultaneously. Report of a Case This 53-year-old woman had a four-year history of arthralgia and myalgia and a three-year history of a "sandy" sensation in the eyes, polydipsia,

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