Product Development Partnerships Hit Their Stride: Lessons From Developing A Meningitis Vaccine For Africa
- 1 June 2011
- journal article
- Published by Health Affairs (Project Hope) in Health Affairs
- Vol. 30 (6) , 1058-1064
- https://doi.org/10.1377/hlthaff.2011.0295
Abstract
The Meningitis Vaccine Project, a so-called product development partnership, developed a new vaccine against bacterial meningitis, an inflammation of brain tissues that causes an estimated 10,000 deaths among African children and young people each year. The vaccine—known as MenAfriVac and specifically targeted for use in low-income countries in Africa—was designed to be made available to governments at a price of fifty cents per dose. The Meningitis Vaccine Project is an example of how product development partnerships have reinvigorated research on vaccines for neglected diseases. These partnerships disperse the multiple tasks of product development across a network of partners that are best suited for each task. The vaccine was rapidly embraced by African health officials, and in its first few weeks on the market, in late 2010, more than nineteen million people in Burkina Faso, Mali, and Niger were vaccinated.Keywords
This publication has 11 references indexed in Scilit:
- A Business Plan To Help The ‘Global South’ In Its Fight Against Neglected DiseasesHealth Affairs, 2009
- The Meningitis Vaccine ProjectVaccine, 2007
- Safety, immunogenicity, and antibody persistence of a new meningococcal group A conjugate vaccine in healthy Indian adultsVaccine, 2007
- The International AIDS Vaccine Initiative (IAVI) in a Changing Landscape of Vaccine Development: A Public/Private Partnership as Knowledge Broker and IntegratorThe European Journal of Development Research, 2007
- The real cost of an affordable vaccine for meningococcus AThe Lancet, 2003
- The real cost of an affordable vaccine for meningococcus A.The Lancet, 2003
- Meningococcal conjugate vaccine for Africa: a model for development of new vaccines for the poorest countriesThe Lancet, 2003
- Synthesis of a conjugate vaccine composed of pneumococcus type 14 capsular polysaccharide bound to pertussis toxinInfection and Immunity, 1992
- Comparative immunogenicity of conjugates composed of the Staphylococcus aureus type 8 capsular polysaccharide bound to carrier proteins by adipic acid dihydrazide or N-succinimidyl-3-(2-pyridyldithio)propionateInfection and Immunity, 1992