Reexamination of Glucose-6-Phosphatase Activity in the Brain in Vivo: No Evidence for a Futile Cycle
- 5 July 1985
- journal article
- research article
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 229 (4708) , 60-62
- https://doi.org/10.1126/science.2990038
Abstract
Glucose-6-phosphatase activity in the rat brain in vivo was estimated by measuring the differential loss of tritium and carbon-14 from the glucose pool labeled by a mixture of [2- 3 H]glucose and [U- 14 C]glucose. The results provide no evidence of significant dephosphorylation of glucose-6-phosphate and do not support the hypothesis of a futile cycle involving glucose-6-phosphatase activity in the brain.This publication has 20 references indexed in Scilit:
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