Heterogeneity of Porcine Somatotropin
- 1 January 1982
- journal article
- research article
- Published by Walter de Gruyter GmbH in Hoppe-Seyler´s Zeitschrift Für Physiologische Chemie
- Vol. 363 (1) , 179-186
- https://doi.org/10.1515/bchm2.1982.363.1.179
Abstract
A chromatographic method is pressented by which highly purified porcine somatotropin can be separated preparatively into 5-subfractions. The rechromatograhped subfractions show comparable biological activities and molecular sizes, but they differ characteristically in the polyacrylamide gel electrophoresis and in the isoelectric focusing. Relatively small differences were found in the amino acid composition of these fractions. The question is discussed whether the term multiple forms or isohormones of porcine somatotropin is suitable for the growth promoting fractions.This publication has 4 references indexed in Scilit:
- The 20,000-dalton variant of human growth hormone: Location of the amino acid deletionsBiochemical and Biophysical Research Communications, 1980
- Preparation and Characteristics of Porcine Growth HormoneHoppe-Seyler´s Zeitschrift Für Physiologische Chemie, 1979
- Use of Electrophoresis and Gel Filtration to Characterize Human Pituitary Somatotropin Preparations after StorageHormone Research, 1979
- DISC ELECTROPHORESIS – II METHOD AND APPLICATION TO HUMAN SERUM PROTEINS*Annals of the New York Academy of Sciences, 1964