Cell-Active Dual Specificity Phosphatase Inhibitors Identified by High-Content Screening
Open Access
- 1 August 2003
- journal article
- research article
- Published by Elsevier in Chemistry & Biology
- Vol. 10 (8) , 733-742
- https://doi.org/10.1016/s1074-5521(03)00170-4
Abstract
No abstract availableKeywords
This publication has 28 references indexed in Scilit:
- Overexpression of mitogen-activated protein kinase phosphatases MKP1, MKP2 in human breast cancerCancer Letters, 2002
- Dual-specificity phosphatases as targets for antineoplastic agentsNature Reviews Drug Discovery, 2002
- Expression of mitogen‐activated protein kinase phosphatase‐1 (MKP‐1) in primary human ovarian carcinomaInternational Journal of Cancer, 2002
- Discovery and Biological Evaluation of a New Family of Potent Inhibitors of the Dual Specificity Protein Phosphatase Cdc25Journal of Medicinal Chemistry, 2001
- Spatial Analysis of Key Signaling Proteins by High-content Solid-phase Cytometry in Hep3B Cells Treated with an Inhibitor of Cdc25 Dual-specificity PhosphatasesPublished by Elsevier ,2001
- Protein phosphatases and the regulation of mitogen-activated protein kinase signallingCurrent Opinion in Cell Biology, 2000
- Inhibition of Hepatoma Cell Growth in Vitro by Arylating and Non-arylating K Vitamin AnalogsPublished by Elsevier ,1999
- Tyrosine Phosphorylation of the Proto-Oncoprotein Raf-1 Is Regulated by Raf-1 Itself and the Phosphatase Cdc25AMolecular and Cellular Biology, 1999
- Cell cycle arrest mediated by the MEK/mitogen-activated protein kinase pathwayProceedings of the National Academy of Sciences, 1997
- CDC25 Phosphatases as Potential Human OncogenesScience, 1995