Role of sympathetic nervous system in immobilization- and cold-induced brown adipose tissue thermogenesis in rats.
Open Access
- 1 January 1984
- journal article
- research article
- Published by Physiological Society of Japan in The Japanese Journal of Physiology
- Vol. 34 (1) , 103-111
- https://doi.org/10.2170/jjphysiol.34.103
Abstract
The role of the sympathetic nervous system in 10-min cold (5°C)- or 2-min immobilization-induced thermogenesis in brown adipose tissue (BAT) was studied in warm(25°C)-acclimated rats. Both cold- and immobilization-stresses increased heat production (M), interscapular brown adipose tissue temperature (Tbat), and colonic temperature (Tcol). Resulting from both stresses, the increase in Tbat was greater than that in Tcol, the differences (ΔTbat) becoming approximately 0.48 and 0.46°C by the cold exposure and the immobilization, respectively. After sympathectomy, Tbat and ΔTbat did not change on immobilization but increased significantly on the cold exposure. ΔTbat was 0.31°C in the sympathectomized rats at the end of the cold exposure period. Immobilization-induced BAT thermogenesis may be mainly controlled by the sympathetic nervous system. On the other hand cold-induced BAT thermogenesis seems to be controlled by certain hormonal factors as well as the sympathetic nervous system.Keywords
This publication has 1 reference indexed in Scilit:
- Heat Balance during Physical Restraint in RatsThe Japanese Journal of Physiology, 1979