The Molecular Epidemiology of Streptococcus pneumoniae with Quinolone Resistance Mutations

Abstract
Background. The purpose of this study was to determine the prevalence of fluoroquinolone resistance and quinolone resistance—determining region (QRDR) mutations among Streptococcus pneumoniae isolates in the United States during the period of 2001–2002. A second objective was to examine the genetic relatedness of pneumococcal isolates with parC and/or gyrA mutations during the period of 1994–2002.

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