1H NMR Thermodynamical Analysis of the Interactions of Proflavine with Self-Complementary Deoxytetranucleotides of Different Base Sequence
- 1 March 1994
- journal article
- research article
- Published by Taylor & Francis in Nucleosides and Nucleotides
- Vol. 13 (1-3) , 657-671
- https://doi.org/10.1080/15257779408013270
Abstract
Enthalpies and entropies of complex formation (1:1, 2:1, 1:2, and 2:2 complexes) between proflavine and tetranucleotides of different base sequence have been determined by 500 MHz proton NMR chemical shifts, enabling the contributions to be differentiated for the formation of different types of complexes in solution. Comparison of the calculated thermodynamical parameters has lead to an understanding of the nature of the intermolecular interactions responsible for the formation of dye complexes with the different tetranucleotides.Keywords
This publication has 16 references indexed in Scilit:
- Investigation of interaction of proflavine with deoxytetraribonucleoside triphosphate 5'-d(ApCpGpT) by the method of 1H-NMR spectroscopyBiopolymers and Cell, 1991
- 1D- and 2D-1H NMR investigation of self-association of deoxytetraribonucleoside triphosphates of different base sequence in aqueous solutionBiopolymers and Cell, 1991
- Temperature dependence of enthalpy changes for ethidium and propidium binding to DNA: Effect of alkylamine chainsBiopolymers, 1990
- 1H-nmr studies of a monointercalating drug into a d(CpGpApTpCpG)2 minihelixBiopolymers, 1989
- Proton and phosphorus-31 NMR investigations of actinomycin D binding selectivity with oligodeoxyribonucleotides containing multiple adjacent d(GC) sitesBiochemistry, 1988
- 1H-nmr studies of a monointercalating drug into a d[CpGpCpG]2 minihelixBiopolymers, 1987
- Thermodynamics of the daunomycin–DNA interaction: Ionic strength dependence of the enthalpy and entropyBiopolymers, 1985
- Anthracycline-binding induced Dna stiffenin, bending and elongation; stereochemical implications from viscometic investigationsNucleic Acids Research, 1983
- The molecular basis for complexation of adriamycin with flavin mononucleotide and flavin adenine dinucleotideArchives of Biochemistry and Biophysics, 1981
- Heat capacity and entropy changes in processes involving proteins.Proceedings of the National Academy of Sciences, 1977