Concurrent infectious mononucleosis and measles: a potentially life-threatening association sharing underlying immunodeficiency
- 1 May 2003
- journal article
- case report
- Published by Wolters Kluwer Health in The Pediatric Infectious Disease Journal
- Vol. 22 (5) , 470-471
- https://doi.org/10.1097/01.inf.0000066873.64509.51
Abstract
We report lethal interstitial pneumonia in an 18-year-old young man with measles infection following recent infectious mononucleosis. We speculate that the documented T cell immune impairment caused by the concurrent Epstein-Barr and measles viral infections (as expressed by a proportionately low CD4+ lymphocyte count) was responsible for the complicated clinical course and unfavorable outcome.Keywords
This publication has 8 references indexed in Scilit:
- Measles Virus Exploits Dendritic Cells to Suppress CD4+ T-Cell Proliferation via Expression of Surface Viral Glycoproteins Independently of T-Cell Trans-infectionCellular Immunology, 2001
- Diagnosis of Atypical Cases of Infectious MononucleosisClinical Infectious Diseases, 2001
- Mechanism of Measles Virus–Induced Suppression of Inflammatory Immune ResponsesImmunity, 2001
- Familial Cases of Severe Measles Pneumonia.Internal Medicine, 2000
- Atypical CD3+ CD4low Cell Population in a Boy with Fatal EBV–InfectionInternational Archives of Allergy and Immunology, 1999
- Modulation of Immune System Function by Measles Virus Infection: Role of Soluble Factor and Direct InfectionJournal of Virology, 1998
- Cell-Mediated Immunity in Infectious MononucleosisPublished by Springer Nature ,1989