Mortality, morbidity, and patterns of recurrence after abdominoperineal resection for cancer of the rectum

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Abstract
Records of 230 patients who underwent abdominoperineal resection between 1963-1976 were reviewed. The median age of the patients was 62 yr. The mortality rate was 1.7% and the morbidity rate was 61%. Patients (180) were followed for 5-13 years to identify patterns of recurrence. Ten-year survival for Dukes'' A, B and C lesions was 83, 57 and 31%, respectively. Seventy-eight patients (43%) had recurrent cancer; 10% had local lesions and 33% had distant lesions. Dukes'' B lesions had a greater latency for local recurrence than Dukes'' C lesions. Dukes'' A lesions with distant recurrence had a greater latency than Dukes'' B or C lesions. Once recurrence was established, the survival rate was not significantly different, regardless of Dukes'' stage or local or distant site. Radiation therapy for established local recurrence or chemotherapy for established distant recurrence did not seem to alter survival rates.