Abstract
172 liver samples from infants were analysed chemically for iron concentration, and histochemically for the presence of iron staining. A closer correlation was found between the amount of iron estimated chemically, and the presence of diffuse cytoplasmic staining than with the presence of granular staining. At levels of less than 5 mg/100 gm there was neither granular nor cytoplasmic staining present. Cytoplasmic staining was found in all sections from livers with an iron concentration of more than 30 mg/100 gm. Granular staining was not always seen above a level of 30 mg/100 gm, and some sections from livers with iron concentrations as high as 41 and 58 mg/100 gm, showed only cytoplasmic staining.

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