Is captopril effective in primary pulmonary hypertension?.
- 1 January 1982
- journal article
- research article
- Published by Japanese Circulation Society in Japanese Circulation Journal
- Vol. 46 (10) , 1095-1097
- https://doi.org/10.1253/jcj.46.1095
Abstract
Several vasodilating agents have been used for the treatment of primary pulmonary hypertension (PPH). No effective therapy is currently available for this distressful disease. An angiotensin-I converting enzyme inhibitor, captopril, was used for one woman suffering from PPH [primary pulmonary hypertension]. Her initial treatment with furosemide, digoxin and spironolactone showed little effect. Further administration of captopril improved her clinical condition from NYHA [New York Heart Association] IV to II and made it possible to treat her at the out-clinic. No adverse effect was found. Captopril is apparently one of the effective drugs in the treatment of PPH.This publication has 4 references indexed in Scilit:
- Immediate and sustained hemodynamic and clinical improvement in chronic heart failure by an oral angiotensin-converting enzyme inhibitor.Circulation, 1980
- Oral Hydralazine Therapy for Primary Pulmonary HypertensionNew England Journal of Medicine, 1980
- Effects of the converting enzyme inhibitor (SQ 20881) on the pulmonary circulation in manThe American Journal of Medicine, 1979
- Primary Pulmonary Hypertension Treated with Oral PhentolamineAnnals of Internal Medicine, 1979