A three year follow-up of chemotherapy with oxamniquine in a Brazilian community with endemic schistosomiasis mansoni
- 1 January 1981
- journal article
- Published by Oxford University Press (OUP) in Transactions of the Royal Society of Tropical Medicine and Hygiene
- Vol. 75 (2) , 234-238
- https://doi.org/10.1016/0035-9203(81)90323-0
Abstract
Oral oxamniquine was tested as a control strategy for endemic schistosomiasis in a rural area of Bahia, Brazil. Adults were treated with a single dose (12·5 to 15 mg per kg) and children (Schistosoma mansoni infection to be high and stable. 33 months after the chemotherapy the prevalence was 41% and for infected individuals the geometric mean egg count was 121 epg, a decline of respectively 35% and 40% from pre-treatment levels for each index. Chemotherapy of infected persons with oxamniquine protected the community as a whole from high worm burdens for almost three years, although at this point the prevalence began to rise towards pretreatment levels.Keywords
This publication has 2 references indexed in Scilit:
- Convulsão associada ao uso de Oxamniquine: relato de um casoRevista da Sociedade Brasileira de Medicina Tropical, 1976
- The Intensity and Effects of Infection with Schistosoma Mansoni in a Rural Community in Northeast BrazilThe American Journal of Tropical Medicine and Hygiene, 1976