Extracorporeal Maintenance of Circulation and Respiration

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Abstract
The numerous pumps and oxygenators designed to assume temporarily the functions of the heart and lungs are presented with remarks on their effectiveness in avoiding damage to the blood and in the exchange of O2 and CO2. The variations in hemodynamics and metabolism encountered during the artificial perfusion of the entire body are considered together with the effects produced upon the blood and other organs. These observations are drawn from data obtained both in the experimental animal and from clinical experience. A number of conclusions are compared with those made from data obtained by other means in the intact organism dependent upon its own heart and respiratory system.

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