The Ability of Smooth and Rough Strains of Streptococcus Pneumoniae to Activate Human Complement by the Alternative Pathway
- 1 February 1978
- journal article
- research article
- Published by Microbiology Society in Journal of Medical Microbiology
- Vol. 11 (1) , 7-14
- https://doi.org/10.1099/00222615-11-1-7
Abstract
SUMMARY Three capsulate pneumococcal strains of serotypes 1, 2 and 3, and one non-capsulate strain of serotype 47, were found to activate human complement by the alternative pathway to a similar extent over the concentration range examined. Nevertheless, the capsulate strains, in contrast to the non-capsulate, are known to require complement attachment for phagocytosis and it is therefore postulated that the toxic by-products released cause the wave of oedema characteristic of pneumococcal lobar pneumonia.This publication has 1 reference indexed in Scilit:
- Quantitative estimation of proteins by electrophoresis in agarose gel containing antibodiesAnalytical Biochemistry, 1966